Case Studies in Clinical Biochemistry

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clinical biochemistry

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The book deals with analytical biochemical tests and consequences for these topics,it deals with all analytical methods and cklinical as[pects,procedures and stastical analysis

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case studies in clinical biochemistry free download

professor Tareq abdhulkadhum naser Alasadi

THEbook discuss the type of pollution and marine pollution ,the factors affecting pollution ,also the toxicity and detoxification s.

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The study was aimed to determined hepatocytes toxicity of propachlor pesticides. The effect was studied in mammalian system (mice) depended on evaluating the enzymatic activity of liver function tests (LFTs) enzymes: alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphate (ALP). The results showed that LFTs enzymes decreased after seven days of gulping mice. Conclusion, propachlor showed acute liver damage that reflected from LFTs activity when comparison with both vitamin C and phosphate buffer solution as a control.

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this is a reserch of pollution.

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Biochemistry is the fascinating science, the Basis of Medicine,extensively useful to understand the diseases at molecular level This paper aims in giving state-of-the-knowledge review on liver functions and tests by descriptive diagrams and flow charts The article gives a bird?s eye view on various basic Biochemical aspects on functions of liver and metabolic reactions involved along with panel of tests. Imbalance /dysfunction / malfunctions of metabolic reactions of liver lead to diseases with clinical manifestations Disorders, Biochemical basis of the disorders, salient biochemical parameters, their levels in health and disease at one roof, aids the budding doctors to diagnose for onward appropriate treatments in treating the diseases.

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Case Studies In Clinical Biochemistry

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Case Studies In Clinical Biochemistry

Case Studies In Clinical Biochemistry written by Dylan E. Jones and has been published by CreateSpace this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-14 with categories.

Thought-provoking and accessible in approach, this updated and expanded second edition of the Case Studies in Clinical Biochemistry provides a user-friendly introduction to the subject, Taking a clear structural framework, it guides the reader through the subject's core elements. A flowing writing style combines with the use of illustrations and diagrams throughout the text to ensure the reader understands even the most complex of concepts. This succinct and enlightening overview is a required reading for advanced graduate-level students. We hope you find this book useful in shaping your future career. Feel free to send us your enquiries related to our publications to [email protected] Rise Press

Essentials Of Medical Biochemistry

Essentials Of Medical Biochemistry

Essentials Of Medical Biochemistry written by N. V. Bhagavan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-24 with Science categories.

Essentials of Medical Biochemistry, Second Edition: With Clinical Cases is the most condensed, yet detailed biochemistry overview available on the topic. It presents contemporary coverage of the fundamentals of biochemistry, emphasizing relevant physiologic and pathophysiologic biochemical concepts. Pivotal clinical case studies aid in understanding basic science in the context of diagnosis and treatment of human diseases, and the text illuminates key topics in molecular immunology and hemostasis. Users will find basic and fundamental concepts that will aid students and professionals in biochemistry, medicine, and other healthcare disciplines. the text is a useful refresher that will help users meet USMLE and other professional licensing examination requirements, providing thorough introductions, key points, multicolored illustrations of chemical structures and figures, fact-filled tables, and recommended reading lists. Presents essential biochemical concepts within the context of their biological functions Contains key clinical case studies in each chapter to enhance understanding of basic science and aid in further comprehension Offers instructional overview figures, flowcharts, tables and multicolored illustrations Includes integrated, recommended reading reference lists within the text Provides an online ancillary package inclusive of PowerPoint images and more than 500 study questions to aid in comprehension and USMLE exam preparation

Clinical Biochemistry E Book

Clinical Biochemistry E Book

Clinical Biochemistry E Book written by Allan Gaw and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-07 with Medical categories.

This edition covers all aspects of the subject needed by medical students. It is a volume in the Illustrated Colour Text series, with the subject matter divided into double-page spreads; this makes the information very accessible to the reader. Full use is made of flow charts and other graphics; clinical "boxes;" summary points; case histories; and clinical photographs. The whole orientation of the book is to concentrate on how clinical biochemistry relates to the care of the patient and to ensure that the medical student understands how to interpret laboratory. Covers clinical biochemistry from the point of view of the clinician using the diagnostic service Presents topics in easily accessible two-page spreads Includes mini case histories, key point boxes, flowcharts, and summary points Well illustrated with four-color drawings and clinical photographs New appendix added of annotated web resources for students to take further many of the topics covered in the book. To reflect the difficulties people have sometimes in analyzing hyper- and hypo-kalaemia, the existing spread is split into two - one spread on hyperkalaemia and another on hypokalaemia. The spread on hypertension will be revised and updated to reflect the fact that biochemistry is used as much or more in guiding treatment as it is in screening for secondary hypertension. Spreads on Myocardial Infarction, Cancer and Tumour Markers will all substantially revised and updated.

Tietz Textbook Of Laboratory Medicine E Book

Tietz Textbook Of Laboratory Medicine E Book

Tietz Textbook Of Laboratory Medicine E Book written by Nader Rifai and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-03 with Medical categories.

Use THE definitive reference for laboratory medicine and clinical pathology! Tietz Textbook of Laboratory Medicine, 7th Edition provides the guidance necessary to select, perform, and evaluate the results of new and established laboratory tests. Comprehensive coverage includes the latest advances in topics such as clinical chemistry, genetic metabolic disorders, molecular diagnostics, hematology and coagulation, clinical microbiology, transfusion medicine, and clinical immunology. From a team of expert contributors led by Nader Rifai, this reference includes access to wide-ranging online resources on Expert Consult — featuring the comprehensive product with fully searchable text, regular content updates, animations, podcasts, over 1300 clinical case studies, lecture series, and more. Authoritative, current content helps you perform tests in a cost-effective, timely, and efficient manner; provides expertise in managing clinical laboratory needs; and shows how to be responsive to an ever-changing environment. Current guidelines help you select, perform, and evaluate the results of new and established laboratory tests. Expert, internationally recognized chapter authors present guidelines representing different practices and points of view. Analytical criteria focus on the medical usefulness of laboratory procedures. Use of standard and international units of measure makes this text appropriate for any user, anywhere in the world. Expert Consult provides the entire text as a fully searchable eBook, and includes regular content updates, animations, podcasts, more than 1300 clinical case studies, over 2500 multiple-choice questions, a lecture series, and more. NEW! 19 additional chapters highlight various specialties throughout laboratory medicine. NEW! Updated, peer-reviewed content provides the most current information possible. NEW! The largest-ever compilation of clinical cases in laboratory medicine is included on Expert Consult. NEW! Over 100 adaptive learning courses on Expert Consult offer the opportunity for personalized education.

Clinical Studies In Medical Biochemistry

Clinical Studies In Medical Biochemistry

Clinical Studies In Medical Biochemistry written by Robert H. Glew and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Biochemistry categories.

This text uses a case-study approach to present the fundamentals of biochemistry and molecular biology in the context of human disease to students who will be involved in patient care. The 32 cases, carefully selected to cover common diseases and important principles, are supplemented by clinical descriptions of each disease and a comprehensive discussion of the underlying pathophysiological mechanisms and associated enzymatic and chemical alterations in tissues and body fluids. The Second Edition differs from its predecessor in several respects. It features seven new chapters on diseases not covered before. The Biochemical Perspectives section of each chapter has been expanded to include pertinent information on the molecular biology of each disease. More chapters are written by authors from outside the U.S., and Dr. Glew has a new co-editor. The diseases covered include those caused by viruses (hepatitis B, HIV), microorganisms (diphtheria), environmental toxins (e.g. lead), cardiovascular abnormalities (myocardial infarction), genetic mutations (hereditary spherocytosis, Gaucher disease, sickle-cell anemia, chronic granulomatous disease), endocrine system disorders (hypertension, Cushing's syndrome), and nutritional deficiencies (rickets). Chapters follow a consistent format. A detailed case report describes the history, pertinent clinical laboratory data, histological findings, and physical characteristics. It is followed by a diagnosis section, which covers biochemical structures and the formulae of enzyme-catalyzed reactions, and describes the definitive method for confirming diagnosis. A discussion of molecular perspectives provides a detailed account of the normal processes and reactions pertaining to the case, along with the mechanism of the disease. The therapy is summarized and the likely prognosis is outlined. Each chapter concludes with discussion questions and a brief bibliography listing informative reviews and key publications. This text is intended for medical schools where biochemistry is taught though the study of actual clinical cases, and will be useful to medical students, graduate students in the biomedical sciences, and practicing physians taking refresher courses.

A Case Oriented Approach Towards Biochemistry

A Case Oriented Approach Towards Biochemistry

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Presented as case studies, this book provides students with up to date, logical coverage of basic biochemistry with normal and abnormal aspects of physiological chemistry. Each section features case studies discussing different disorders and conditions in topics including chemistry and metabolism of carbohydrates, lipids, amino acids, proteins and nucleotides, as well as vitamins, minerals, hormones, diet and detoxification. Each case is presented in a problem-solving approach, describing the history, clinical manifestations and laboratory findings of the disease, assisted by detailed illustrations. The final sections offer normal laboratory reference values and case studies and answers for self assessment. Key points Case studies presented in problem solving approach covering history, clinical manifestations and laboratory findings of biochemistry of different diseases and conditions Separate sections dedicated to AIDS, cancer, molecular biology, organ function tests and water and electrolyte imbalance Includes normal laboratory reference values and case studies for self assessment

Tietz Textbook Of Clinical Chemistry And Molecular Diagnostics

Tietz Textbook Of Clinical Chemistry And Molecular Diagnostics

Tietz Textbook Of Clinical Chemistry And Molecular Diagnostics written by Nader Rifai and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-16 with Medical categories.

The Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 6th Edition provides the most current and authoritative guidance on selecting, performing, and evaluating the results of new and established laboratory tests. This classic clinical chemistry reference offers encyclopedic coverage detailing everything you need to know, including: analytical criteria for the medical usefulness of laboratory tests, variables that affect tests and results, laboratory medicine, applications of statistical methods, and most importantly clinical utility and interpretation of laboratory tests. It is THE definitive reference in clinical chemistry and molecular diagnostics, now fully searchable and with quarterly content updates, podcasts, clinical cases, animations, and extended content online through Expert Consult. Analytical criteria focus on the medical usefulness of laboratory procedures. Reference ranges show new approaches for establishing these ranges — and provide the latest information on this topic. Lab management and costs gives students and chemists the practical information they need to assess costs, allowing them to do their job more efficiently and effectively. Statistical methods coverage provides you with information critical to the practice of clinical chemistry. Internationally recognized chapter authors are considered among the best in their field. Two-color design highlights important features, illustrations, and content to help you find information easier and faster. NEW! Internationally recognized chapter authors are considered among the best in their field. NEW! Expert Consult features fully searchable text, quarterly content updates, clinical case studies, animations, podcasts, atlases, biochemical calculations, multiple-choice questions, links to Medline, an image collection, and audio interviews. You will now enjoy an online version making utility of this book even greater. UPDATED! Expanded Molecular Diagnostics section with 12 chapters that focus on emerging issues and techniques in the rapidly evolving and important field of molecular diagnostics and genetics ensures this text is on the cutting edge and of the most value. NEW! Comprehensive list of Reference Intervals for children and adults with graphic displays developed using contemporary instrumentation. NEW! Standard and international units of measure make this text appropriate for any user — anywhere in the world. NEW! 22 new chapters that focus on applications of mass spectrometry, hematology, transfusion medicine, microbiology, biobanking, biomarker utility in the pharmaceutical industry and more! NEW! Expert senior editors, Nader Rifai, Carl Wittwer and Rita Horvath, bring fresh perspectives and help ensure the most current information is presented. UPDATED! Thoroughly revised and peer-reviewed chapters provide you with the most current information possible.

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Harper's Illustrated Biochemistry, 30e

Chapter 57:  Biochemical Case Histories

David A. Bender

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Introduction.

After studying this chapter, you should be able to:

Use your knowledge to explain the underlying biochemical defects in diseases.

FIGURE 57–1

Plasma glucose in the patient and a control subject after a test dose of glucose .

image

FIGURE 57–2

Insulin measured by radio-immunoassay and biological assay before and after treatment of plasma samples with trypsin .

image

What does this information suggest about the processes that occur in the synthesis of insulin?

What is likely to be the underlying biochemical basis of the patient’s problem?

What is the likely biochemical basis of the patient’s problem, which led to his emergency hospitalization?

What additional test(s) might you request to confirm your assumption?

What emergency treatment would you suggest?

How much GSH is oxidized per mol of acetylphenylhydrazine added?

nd , not detectable, ie, below the limits of detection.

Figures show dpm, mean ± sd for 5 replicate incubations.

Sodium ascorbate (which undergoes a nonenzymic reaction in air to produce H 2 O 2 )

Acetylphenylhydrazine (which is known to precipitate hemolysis in sensitive subjects, and depletes reduced glutathione)

Methylene blue (which oxidizes NADPH)

What conclusions can you draw from these results?

What conclusions can you draw from these observations?

Can you explain the biochemical basis of the patient’s condition?

When she was fed a relatively high protein meal (she became grizzly, lethargic, and irritable). A blood sample taken after such a meal showed significant hyperammonemia (130 μmol/L), but normal glucose (5.5 mmol/L).

When she was fasted for more than the normal overnight fast, with or without the infusion of β-hydroxybutyrate.

What is the likely biochemical basis of the patient’s problem? To what extent can you account for her various metabolic problems from the information you are given?

What dietary manipulation(s) would be likely to maintain her in good health, and prevent further emergency hospital admissions?

Lactate, pyruvate, and alanine

Propionate, hydroxypropionate, and propionyl glycine

Methylcitrate

Tiglate and tiglylglycine

3-Methyl crotonate, 3-methylcrotonylglycine, and 3-hydroxyisovalerate

Can you account for the biochemical basis of the patient’s problem?

Source: From data reported by Coore HG, Randle PJ: Biochemical J 1964;93:66–77.

Hexokinase is expressed in all tissues; it has a K m for glucose of ~0.15 mmol/L

Glucokinase is expressed only in liver and the β-cells of the pancreas; it has a K m for glucose of ~20 mmol/L

What effect will changes in the plasma concentration of glucose have on the rate of formation of glucose- 6-phosphate catalyzed by hexokinase?

What effect will changes in the plasma concentration of glucose have on the rate of formation of glucose- 6-phosphate catalyzed by glucokinase?

What is the importance of glucokinase in the liver?

Source: From data reported by Froguel P, et al: N Engl J Med 1993;328:697–702.

What are the amino acid changes associated with each mutation in the gene?

Why do the mutations affecting codons 4, 10, and 116 have no effect on the people involved?

What conclusions can you draw from this information?

What conclusions can you draw from this information about the probable role of glucokinase in the β-cells of the pancreas?

Can you deduce the way in which the β-cells of the pancreas sense an increase in plasma glucose and signal the secretion of insulin?

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A Case Oriented Approach Towards Biochemistry by Namrata Chhabra PDF is one of the best book for quick review. It is very good book to study a day before your exam. It can also cover your viva questions and will help you to score very high.

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The book A Case Oriented Approach towards Biochemistry provides complete background knowledge of a disease process and at the same time, there is an excellent and updated correlation of the clinical database with the basic fundamental facts. It provides a platform for an acquisition of knowledge of biochemistry through a case-oriented approach. Understanding of biochemistry concepts must be strong as it is encroaching in every area from pathophysiology to the investigations and treatment rationale. The case studies given in this book are structured in such a way that it takes into an investigating atmosphere connecting from panel-to-panel and establishing links between the symptoms and the underlying disease. It covers all the diseases or disorders caused by synthesis or degradation of carbohydrates, lipids, proteins, amino acids, nucleotide, oxygen, heme, hormones, hemoglobinopathies, water and electrolyte (balance or imbalance) and so on. All the case studies are covered with a through history, clinical manifestations, laboratory findings, physiological and biochemical deviations which may help to frame a diagnosis and plan a suitable treatment.

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Clinical Case Discussion in Biochemistry

Clinical Case Discussion in Biochemistry

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Case studies in clinical biochemistry.

Case Studies in Clinical Biochemistry

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Clinical Biochemistry is about patients - how we investigate their signs and symptoms, how we diagnose their illnesses and how we treat them. In this book the authors present a series of clinical cases, all based on real patients, and invite the reader to answer key questions using their knowledge and experience of each topic. Each case and its questions are accompanied by the authors' detailed answers, which can be found by simply turning the page. As such, it is an ideal revision aid for those studying Medicine, Nursing and Biomedical Sciences and for those preparing for post-graduate membership examinations.

Essentials of Medical Biochemistry

Essentials of Medical Biochemistry

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Expert biochemist N.V. Bhagavan’s new work condenses his successful Medical Biochemistry texts along with numerous case studies, to act as an extensive review and reference guide for both students and experts alike. The research-driven content includes four-color illustrations throughout to develop an understanding of the events and processes that are occurring at both the molecular and macrolecular levels of physiologic regulation, clinical effects, and interactions. Using thorough introductions, end of chapter reviews, fact-filled tables, and related multiple-choice questions, Bhagavan provides the reader with the most condensed yet detailed biochemistry overview available. More than a quick survey, this comprehensive text includes USMLE sample exams from Bhagavan himself, a previous coauthor. * Clinical focus emphasizing relevant physiologic and pathophysiologic biochemical concepts * Interactive multiple-choice questions to prep for USMLE exams * Clinical case studies for understanding basic science, diagnosis, and treatment of human diseases * Instructional overview figures, flowcharts, and tables to enhance understanding

Human Pathobiochemistry

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This textbook uses a case-study approach to present the core principles of biochemistry and molecular biology in the context of human disease to students who will be involved in patient care. The 29 clinical cases have been carefully selected to cover key scientific concepts and some common, and other not so common, diseases. While the principal focus is on topics relating to metabolic disease, further subjects such as connective tissue disorders, neurological disorders, auto-inflammatory disorders, infective diseases, and cancer are also addressed. Each chapter provides a specific patient report that includes the natural history, pertinent clinical laboratory data, physical findings, subsequent diagnosis, and therapy. This is followed by a comprehensive discussion of the normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease. Graphical diagrams are provided in each chapter for ease of comprehension.

Clinical Studies in Medical Biochemistry

Clinical Studies in Medical Biochemistry

Download Clinical Studies in Medical Biochemistry Book in PDF, Epub and Kindle

This text uses a case-study approach to present core principles of biochemistry and molecular biology in the context of human disease. The thirty-three cases have been carefully chosen to cover key concepts and common diseases. Each chapter provides a specific patient report that includes relevant history, pertinent clinical laboratory data, physical findings, and subsequent diagnosis. This is followed by a comprehensive discussion of normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease. In this third edition of the book, a new co-editor has aided in the substantially revised and more targeted selection of cases. The whole volume is now clearly focused on intermediary metabolism and other topics central to biochemistry. There are new chapters on topics such as collagen structure, mitochondrial metabolism, and hyperhomocysteinemia and vascular disease. There is also more coverage of nutritional biochemistry, including new chapters on protein-calorie malnutrition, obesity, vitamin A deficiency, and iron metabolism. The best cases were retained from the previous edition, and have been completely rewritten and updated to include recent advances in diagnostic biochemistry and the status of current therapies. Although the first edition was intended primarily for medical students, through the years the book has proven useful for a wide variety of students interested in the health science professions.

Essentials of Medical Biochemistry

Essentials of Medical Biochemistry, Second Edition: With Clinical Cases is the most condensed, yet detailed biochemistry overview available on the topic. It presents contemporary coverage of the fundamentals of biochemistry, emphasizing relevant physiologic and pathophysiologic biochemical concepts. Pivotal clinical case studies aid in understanding basic science in the context of diagnosis and treatment of human diseases, and the text illuminates key topics in molecular immunology and hemostasis. Users will find basic and fundamental concepts that will aid students and professionals in biochemistry, medicine, and other healthcare disciplines. the text is a useful refresher that will help users meet USMLE and other professional licensing examination requirements, providing thorough introductions, key points, multicolored illustrations of chemical structures and figures, fact-filled tables, and recommended reading lists. Presents essential biochemical concepts within the context of their biological functions Contains key clinical case studies in each chapter to enhance understanding of basic science and aid in further comprehension Offers instructional overview figures, flowcharts, tables and multicolored illustrations Includes integrated, recommended reading reference lists within the text Provides an online ancillary package inclusive of PowerPoint images and more than 500 study questions to aid in comprehension and USMLE exam preparation

Handbook of Biochemistry Spotting

Handbook of Biochemistry Spotting

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Clinical biochemistry e book.

Clinical Biochemistry E Book

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Now over 70,000 copies sold! This comprehensively revised edition of Clinical Biochemistry offers essential reading for today’s students of medicine and other health science disciplines – indeed, anyone who requires a concise, practical introduction to the subject. Topics are clearly presented in a series of double-page ‘learning units’, each covering a particular aspect of clinical biochemistry. Four sections provide a core grounding in the subject: Introducing clinical biochemistry gives an insight into how modern hospital laboratories work, and includes an entirely new series of learning units on the interpretation of test results Core biochemistry covers the bulk of routine analyses, and their relevance to the clinical setting Endocrinology provides an overview of endocrine investigations as well as a practical approach to thyroid, adrenal, pituitary and gonadal function testing Specialised investigations embraces an assortment of other topics that students may encounter This edition represents the most radical revision of the book to date. Every learning unit has been examined and updated to reflect current developments and clinical best practice. Entirely new material includes a series of learning units on interpretation and analytical aspects of clinical biochemistry. Coverage of fluid biochemistry is now more comprehensive. New "Want to know more?" links throughout the book point readers to relevant further information. (Printed version) now includes the complete eBook version for the first time – downloadable for anytime access and enhanced with new, interactive multiple choice questions for each section, to test your understanding and aid exam preparation

Case Studies in Clinical Biochemistry

Murphy MJ, Srivastava R and Gaw A. SA Press, June 1, 2012, Paperback, 132 pp, Kindle e-book, ISBN 978-09563242-4-5

Indian Journal of Clinical Biochemistry volume  27 ,  page 426 ( 2012 ) Cite this article

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Each case study consists of a short clinical history accompanied by key clinical findings and laboratory results, and a series of questions. The authors’ detailed answers and explanations to these questions can found by simply turning the page. The case studies and their questions are designed to address key teaching points in Clinical Biochemistry and to do so in the context of real clinical experience. As such it is an ideal revision aid for those studying Medicine, Nursing and Biomedical Sciences and for those preparing for post-graduate membership examinations.

As an important added extra, a unique facebook page has been created to allow readers to access additional educational material not found in the book, and to interact directly with the authors, Michael Murphy, Rajeev Srivastava and Allan Gaw. You may find them on www.facebook.com/ClinicalBiochemistry and you can follow them on twitter @SAPress42.

The 132 page book is available to purchase on amazon. A kindle version is also available for download at $7.43 from www.amazon.com .

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Sharma, P. Case Studies in Clinical Biochemistry. Ind J Clin Biochem 27 , 426 (2012). https://doi.org/10.1007/s12291-012-0254-3

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Published : 14 October 2012

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Clinical Biochemistry - Case Study Example

Clinical Biochemistry Case Study

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Indeed as in the case of James, ischemic heart disease, which is by far the most common form of heart disease in adults, may present with chest discomfort which may be the result of myocardial infarction.Although the clinical history fits with the junior doctor's decision, before taking the decision of administering streptokinase, the doctor would have consulted with the consultant, since the results of biochemical tests in establishing a diagnosis of myocardial infarction may be very misleading in such cases, where even terminal catastrophe may occur.

The ECG is the cornerstone in the diagnosis of acute myocardial infarction (MI). The biochemical test results must be interpreted in light of the findings in the ECG, although both the sensitivity and specificity are limited, but a normal ECG is uncommon in a case of established myocardial infarction, and the junior doctor did not do an ECG. Before taking a decision of administering streptokinase, it would have been mandatory to establish the diagnosis of acute MI and to rule any bleeding lesion, and these tests were not done.

The CK has been done, which is found to be elevated to 250 U/L against 20-200 U/L but in this case more specific CK-MB and Troponin-I would have been advised. The ideal course would have been admit to patient to the hospital and monitor him for deterioration and ECG. Serial markers would have indicated deterioration. Creatine phosphokinase (CK) rises within 4 to 8 h and generally returns to normal by 48 to 72 h. An important drawback of total CK measurement is its lack of specificity for STEMI, as CK may be elevated with skeletal muscle trauma, which may be the case in this patient who sustained a fall, trauma, and bruises.

This may lead to a 2 to 3-fold elevation of CK, which commonly leads to ambiguity and erroneous diagnosis of myocardial infarction. Even initially James could have sustained a stroke which is also a cause of elevated CK. CK-MB is advised in such cases to pinpoint the diagnosis since it is more sensitive and specific for myocardial infarction due to its absence in extracardiac tissues. The differentiation between muscle trauma and myocardial infarction origin of CK-MB can be done through calculation of relative index of CKMB mass: CK activity.

If this is 2.5, a diagnosis of MI is favoured. Again in case of a skeletal muscle injury which may be the initial situation at James' presentation, this ratio is less useful due to elevation in level of total CK. The elevated AST and LDH have been obviously wrongly correlated to the myocardial infarction since these values per se are nonspecific for myocardial infarction. This is probably right since the time course of these elevations suggest that these were found to be elevated following 2 hours 35 minutes from the initial incident of fall.

The values are directly related to the amount of injury of the cardiac cells and AST takes 12 hours and LDH takes 18 hours to be elevated following MI if they are due exclusively to MI. Thus given these facts, it must be stated that while the patient actually

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A Case Oriented Approach Towards Biochemistry by Namrata Chhabra

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Case studies presented in problem solving approach covering history, clinical manifestations and laboratory findings of biochemistry of different diseases and conditions. Separate sections dedicated to AIDS, cancer, molecular biology, organ function tests and water and electrolyte imbalance. Includes normal laboratory reference values and case studies for self assessment. A Case Oriented Approach Towards Biochemistry by Namrata Chhabra PDF

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Health, anatomy, physiology, biochemistry, medicine, surgery, and nursing textbooks will likely be at your side throughout your medical studies, and you’ll be reading through countless scientific papers, but you might want to read something beforehand that gives you insight into the world of medicine in practice – whether that’s research, at the clinic or in the operating room.  The most featured and reviewed on book “ A Case Oriented Approach Towards Biochemistry by Namrata Chhabra PDF ” is available for grabs now here on our website free for students and professionals sole purpose of teaching and education. It has been boasted and proven with thousands of user reviews that it has all the information to make you one of the highly qualified professionals in the world of medicine and its branches. Without a doubt a masterpiece for those who aspire to be doctors or heal those they find in ailment. It is a must read again and again for everyone that can get their hands on this limited edition book. If you are a medical student or are still thinking about it, you will find yourself reading many books like encyclopedia health books. Being a medical student is not easy. Another of the many benefits of reading books is that it reduces stress and anxiety. As a medical student, it is normal for you to feel scared due to being overwhelmed. You’ll be completely focused on the story or advice, which calms you down and makes you happier, especially if you’re reading something happy and moving. When you finish reading, you can be calm enough to look at your problem differently. Every time you read a book, you build some relationship with these characters. Even if you are only different in paper and ink, you are still connected to that character. Sometimes you’re even in their thoughts. This alleviates the feeling of isolation because you feel connected to these characters. It also alleviates feelings of exhaustion and despair when you’re reading something exciting and happy. Download it now.

The Authors

Namrata Chhabra

Namrata Chhabra MD (Biochemistry) Professor and Head, Department of Biochemistry, Sir Seewoosagur Ramgoolam Medical College, Belle Rive, Mauritius Sahil Chhabra MBBS Research Associate, Department of Anesthesiology and Perioperative Medicine, University of Louisville, Kentucky, USA

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iris excellent Reviewed in the United Kingdom on 19 April 2014 a must have if you are doing medical sciences or clinical sciences, the cases are great, the theory and all the test info are just perfect i cant critisice it one bit!

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